Introduction to Parkinson's Science/Q Page 40

What are the symptoms of Parkinson's disease?Edit

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Introduction to Parkinson's Science/Q Page 2 and
Introduction to Parkinson's Science/Q Page 3 and is linked to from 
Introduction to Parkinson's Science/Q Page 50.
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What are the other symptoms of Parkinson's disease?
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Parkinson’s Disease symptoms vary from patient to patient. They can come about in a number of ways:-

Dopamine deficiency Primary symptoms

Movement disorders arise through a reduction in the brain’s capacity to manufacture a consistent supply of this neurotransmitter. Typical of these are uneven gait, stiffness, difficulty in maintaining balance, a resting tremor in the limbs or jaw.

Dopamine deficiency Secondary symptoms

These are derivative of primary symptoms.

For example drooling is the consequence of a build up of saliva in the mouth.

This is a consequence of a reduced rate of swallowing.

This is a consequence of reduced autonomic movements.

Side effects of therapy

An example is dyskinesia – uncontrolled jerking about of the heed and shoulders arising from prolonged use of levodopa.

Symptoms in the second two categories are treatable, even curable without recourse to dopamine replacement therapy. The implication for researchers is that it is worthwhile to evaluate indivdual symptoms, for diagnosticians that each PD patient should be treated as an individual rather than a phenotype, and for patients that all symptoms should be declared in order to optimse diagnosis and treatment.

The following list of PD symptoms is a synthesis from the following sources:-

Dr. Oliver Sachs Awakenings http://www.acamedia.info/literature/alexanders_feast/awakenings/excerpts.htm

Parkinson’ UK http://www.parkinsons.org.uk/default.aspx?page=9739

Web MD http://www.webmd.com/parkinsons-disease/parkinsons-glossary

Michael J. Fox Foundation https://www.michaeljfox.org/glossary.php

National Parkinson Foundation http://www.parkinson.org/Parkinson-s-Disease/Glossary

Readers are invited to improve on individual entries.

A to ZEdit

Links to the symptoms of Parkinson's in alphabetical order:

A B C D E
F - G H I - L M - N O
P - Q R S T U - Z

(Click to go to table for editing)

ReferencesEdit