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Gene transcriptions/Boxes/E2s/Quiz

< Gene transcriptions/Boxes | E2s

E2 box is a lecture as part of the gene transcription series.

File:Schematic representation of the GLε promoter.png
Schematic representation of the GLε promoter shows that the E2 box and STAT6 are in the GLε promoter. Credit: Manabu Sugai, Hiroyuki Gonda, Takashi Kusunoki, Tomoya Katakai, Yoshifumi Yokota and Akira Shimizu.{{fairuse}}

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Quiz

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1 Yes or No, A repeating sequence of nucleotides that forms a transcription or a regulatory signal is called a box.

Yes
No

2 The portion of a promoter in which an E2 box is likely to be found is which of the following?

dispersed promoter
proximal promoter
downstream promoter
distal promoter
enhancer
focused promoter
core promoter

3 Yes or No, The gene RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain.

Yes
No

4 Several promoter elements have been previously identified in eukaryotes, but those cannot account for transcription from most RNA polymerase II-transcribed

.

5 True or False, Some E2 boxes are located in the dispersed promoter.

TRUE
FALSE

6 Which of the following is not a transcriptional characteristic of E2 boxes?

located between nucleotides -8 and +2 relative to the transcriptional start site (+1)
G/A/T-G/C+1-G-T/C-G-G-G/A-A-G/C
in eukaryotes
TATA-less genes
a consensus sequence

7 Complete the text:

A core

element is the

region HY box between

and -60

upstream from the transcription start site.

8 Complete the text:

Match up the type of promoter or promoter element with each of the possibilities below:
TATA box - A
initiator element - B
enhancers and inhibitors - C
downstream elements - D
General transcription factor II D - E
ATA box - F
downstream core promoter

.
includes the transcription start site

.
proximal promoter

.
distal promoter

.
core promoter

usually 25 nucleotides upstream

.

9 Which of the following are phenomena associated with E2 boxes?

transcription of A1BG
directs activator-dependent but TFIID-independent transcription
TATA box-less promoters
initiator element
mediator dependence
core promoter

10 True or False, E2 boxes are found in the promoter regions of at least 1% of human genes.

TRUE
FALSE


Hypotheses

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Main resource: Hypotheses
  1. A1BG is not transcribed by an HY box.

See also

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{{Anthropology resources}}

{{Medicine resources}}{{Phosphate biochemistry}}

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