Gene transcriptions/Elements/EIF4E basals/Quiz

EIF4E basal element is a lecture and an article as part of the gene transcription series.

Eimeria oocysts vary in size, with E. maxima being the largest (about 20 x 30 microns) and E. mitis the smallest (about 14 x 16 microns). Credit: USDA ARS.

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Quiz

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1 Yes or No, The EIF4E basal element, also eIF4E, (4EBE) is a basal promoter element for the eukaryotic translation initiation factor 4E.

Yes
No

2 The portion of a promoter in which an EIF4E basal element is likely to be found is which of the following?

dispersed promoter
proximal promoter
downstream promoter
distal promoter
enhancer
focused promoter
core promoter

3 Yes or No, Interactions between 4EBE and upstream activator sites are position, distance, and sequence dependent.

Yes
No

4 Several promoter elements have been previously identified in eukaryotes, but those cannot account for transcription from most RNA polymerase II-transcribed

5 True or False, Some EIF4E basal elements are located in the dispersed promoter.

TRUE
FALSE

6 Which of the following is not a transcriptional characteristic of EIF4E basal elements?

located between nucleotides -8 and +2 relative to the transcriptional start site (+1)
G/A/T-G/C+1-G-T/C-G-G-G/A-A-G/C
in eukaryotes
TATA-less genes
a consensus sequence

7 Complete the text:

The location of the 4EBE is at the site where the

box should be

.

8 Complete the text:

Match up the type of promoter or promoter element with each of the possibilities below:
TATA box - A
initiator element - B
enhancers and inhibitors - C
downstream elements - D
General transcription factor II D - E
ATA box - F
downstream core promoter

.
includes the transcription start site

.
proximal promoter

.
distal promoter

.
core promoter

usually 25 nucleotides upstream

.

9 Which of the following are phenomena associated with EIF4E basal elements?

transcription of A1BG
directs activator-dependent but TFIID-independent transcription
TATA box-less promoters
initiator element
mediator dependence
core promoter

10 True or False, EIF4E basal elements are found in the promoter regions of at least 1% of human genes.

TRUE
FALSE


Hypotheses

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  1. A1BG is not transcribed by an eIF4E basal element.

See also

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{{Anthropology resources}}

{{Medicine resources}}{{Phosphate biochemistry}}