Gene transcriptions/Elements/EIF4E basals/Quiz

EIF4E basal element is a lecture and an article as part of the gene transcription series.

Eimeria oocysts vary in size, with E. maxima being the largest (about 20 x 30 microns) and E. mitis the smallest (about 14 x 16 microns). Credit: USDA ARS.

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Quiz edit


1 Yes or No, The EIF4E basal element, also eIF4E, (4EBE) is a basal promoter element for the eukaryotic translation initiation factor 4E.


2 The portion of a promoter in which an EIF4E basal element is likely to be found is which of the following?

dispersed promoter
proximal promoter
downstream promoter
distal promoter
focused promoter
core promoter

3 Yes or No, Interactions between 4EBE and upstream activator sites are position, distance, and sequence dependent.


4 Several promoter elements have been previously identified in eukaryotes, but those cannot account for transcription from most RNA polymerase II-transcribed

5 True or False, Some EIF4E basal elements are located in the dispersed promoter.


6 Which of the following is not a transcriptional characteristic of EIF4E basal elements?

located between nucleotides -8 and +2 relative to the transcriptional start site (+1)
in eukaryotes
TATA-less genes
a consensus sequence

7 Complete the text:

The location of the 4EBE is at the site where the

box should be


8 Complete the text:

Match up the type of promoter or promoter element with each of the possibilities below:
TATA box - A
initiator element - B
enhancers and inhibitors - C
downstream elements - D
General transcription factor II D - E
ATA box - F
downstream core promoter

includes the transcription start site

proximal promoter

distal promoter

core promoter

usually 25 nucleotides upstream


9 Which of the following are phenomena associated with EIF4E basal elements?

transcription of A1BG
directs activator-dependent but TFIID-independent transcription
TATA box-less promoters
initiator element
mediator dependence
core promoter

10 True or False, EIF4E basal elements are found in the promoter regions of at least 1% of human genes.


Hypotheses edit

  1. A1BG is not transcribed by an eIF4E basal element.

See also edit

External links edit

{{Anthropology resources}}

{{Medicine resources}}{{Phosphate biochemistry}}