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Gene transcriptions/Boxes/Enhancers/Quiz

< Gene transcriptions/Boxes | Enhancers

E box is a lecture and an article as part of the gene transcription series.

This is an image of Dendromus mysticalis, the chestnut climbing mouse. Credit: Kenneth Worm.

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Quiz

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1 Yes or No, An enhancer is a short region of DNA that can be bound with proteins (namely, the trans-acting factors, much like a set of transcription factors) to enhance transcription levels of genes (hence the name) in a gene cluster.

Yes
No

2 The portion of a promoter in which an E box is likely to be found is which of the following?

dispersed promoter
proximal promoter
downstream promoter
distal promoter
enhancer
focused promoter

3 Yes or No, An E-box (Enhancer Box) is a DNA sequence which usually lies upstream of a gene in a promoter region.

Yes
No

4 Several promoter elements have been previously identified in eukaryotes, but those cannot account for transcription from most RNA polymerase II-transcribed

5 Yes or No, Some E boxes are located in the dispersed promoter.

Yes
No

6 Which of the following is not a transcriptional characteristic of E boxes?

located between nucleotides -8 and +2 relative to the transcriptional start site (+1)
G/A/T-G/C+1-G-T/C-G-G-G/A-A-G/C
in eukaryotes
TATA-less genes
a consensus sequence

7 Complete the text:

An enhancer box usually lies

of a gene in a

region.

8 Complete the text:

Match up the type of promoter or promoter element with each of the possibilities below:
TATA box - A
initiator element - B
enhancers and inhibitors - C
downstream elements - D
General transcription factor II D - E
ATA box - F
downstream core promoter

.
includes the transcription start site

.
proximal promoter

.
distal promoter

.
core promoter

usually 25 nucleotides upstream

.

9 Which of the following are phenomena associated with E boxes?

transcription of A1BG
directs activator-dependent but TFIID-independent transcription
TATA box-less promoters
initiator element
mediator dependence
proximal promoter

10 True or False, E boxes are found in the promoter regions of at least 1% of human genes.

TRUE
FALSE


Hypotheses

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Main resource: Hypotheses
  1. A1BG has an enhancer box.

See also

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{{Anthropology resources}}

{{Medicine resources}}{{Phosphate biochemistry}}

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