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<email_address><span class="nowrap">Contact[[File:At sign.svg|alt=At sign|15px|@|link=]]WikiJMed.org</span></email_address>
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<registrant>WEB-FORM</registrant>
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<journal>
<journal_metadata>
<full_title>WikiJournal of Medicine/Hepatitis E</full_title>
<abbrev_title>Wiki.J.Med.</abbrev_title>
<issn media_type='electronic'>2002-4436 / 2470-6345 / 2639-5347</issn>
<doi_data>
<doi>10.15347/WJM</doi>
<resource>http://www.WikiJMed.org/</resource>
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<journal_issue>
<publication_date media_type='online'>
<year>2019</year>
</publication_date>
<journal_volume>
<volume></volume>
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<issue></issue>
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<journal_article publication_type='full_text'>
<titles>
<title>Hepatitis E</title>
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<person_name sequence='first' contributor_role='author'>
<surname></surname>
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<surname>et al.</surname><affiliation>Wikipedia editors of Hepatitis_E</affiliation><link>https://xtools.wmflabs.org/articleinfo/en.wikipedia.org/Hepatitis_E//2019-07-27</link>
</person_name>
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<publication_date media_type='online'>
<year>2019</year>
</publication_date>
<doi_data>
<doi>10.15347/wjm/2019.003</doi>
<resource>https://en.wikiversity.org/wiki/WikiJournal of Medicine/Hepatitis E</resource>
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<license license-type="open-access">
<license-p>[[File:Open_Access_logo_PLoS_white.svg|11px|link=Wikipedia:Open Access]] [[File:Cc.logo.circle.svg|16px|link=Wikipedia:Creative Commons]]
This is an open access article distributed under the [http://creativecommons.org/licenses/by-sa/3.0/ Creative Commons Attribution ShareAlike License], which permits unrestricted use, distribution, and reproduction, provided the original author and source are credited.</license-p>
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<abstract>
</p>
Hepatitis E is inflammation of the liver caused by infection with the hepatitis E virus. It is one of five known human hepatitis viruses: A, B, C, D, and E. HEV is a positive-sense, single-stranded, nonenveloped, RNA icosahedral virus. HEV has mainly a fecal-oral transmission route. Infection with this virus was first documented in 1955 during an outbreak in New Delhi, India. A preventive vaccine (HEV 239) is approved for use in China. Although hepatitis E often causes an acute and self-limiting infection (the viral infection is temporary and the individual recovers) with low death rates in the western world, it bears a high risk of developing chronic hepatitis in people with a weakened immune system with substantially higher death rates. Organ transplant recipients who receive medications to weaken the immune system and prevent organ rejection are thought to be the main population at risk for chronic hepatitis E. Hepatitis E infection has a clinical course comparable to hepatitis A, but in pregnant women, the disease is more often severe and is associated with a clinical syndrome called fulminant liver failure. Pregnant women, especially those in the third trimester, have a higher rate of death from the disease of around 20%. In total there are 8 genotypes; genotypes 3 and 4 cause chronic hepatitis in the immunosuppressed. Hepatitis E incidence in 2017 was more than 19 million.
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</abstract>
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