Progress and Prospects in Parkinson's Research/Therapy/Research to Clinic
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This topic is for exploring the evident stumbling blocks in the way of turning the results of research into practical and effective treatments and therapies for Parkinson's disease in the clinic. Despite massive effort in laboratories, enormous expense by drug companies and large, expensive clinical trials, relatively few drugs and other therapies have made their way to routine use by the Parkinson's patient community. Essays on the issues and how they might be confronted are welcome as sub pages to this topic.
Why do so many drugs fail at the last hurdle? Is there a serious procedural flaw in drug research? An article reproduced from Spring Times, April 2011. File details
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A interesting animation from the M J Fox Foundation which breaks down the complex process of drug development and translation to the clinic: https://www.michaeljfox.org/foundation/role.html