The Sps is a lecture as part of the gene transcription series and gene transcription course.

Withania somnifera produces Withaferin A, a sterodial lactone known to inhibit Sp1 transcription factor. Credit: Hari Prasad Nadig from Bangalore, India.{{free media}}

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Quiz

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1 Which of the following are phenomena associated with CpG sites?

cytosine nucleotide occurs next to a guanine nucleotide
"—C—phosphate—G—"
CG base-pairing
C and G are found on the same strand of DNA or RNA and are connected by a phosphodiester bond
cytosine being 3 prime to the guanine base
CpG islands
three hydrogen bonds

2 True or False, A repeating sequence of nucleotides that forms a transcription or a regulatory signal is called a box.

TRUE
FALSE

3 Several promoter elements have been previously identified in eukaryotes, but those cannot account for transcription from most RNA polymerase II-transcribed

4 True or False, The Sps are located in the distal promoter.

TRUE
FALSE

5 Which of the following is not a transcriptional characteristic of the Sps?

located between nucleotides -8 and +2 relative to the transcriptional start site (+1)
G/A/T-G/C+1-G-T/C-G-G-G/A-A-G/C
in eukaryotes
TATA-less genes
a consensus sequence

6 True or False, An AGC box contains the nucleotide sequence CGCC.

TRUE
FALSE

7 Which of the following are phenomena associated with Sps?

transcription of A1BG
directs activator-dependent but TFIID-independent transcription
TATA box-less promoters
transcription start site
mediator dependence
core promoter
RNA polymerase II holoenzyme

8 True or False, Sps are found in the promoter regions of about 1% of human genes.

TRUE
FALSE

9 Which of the following are phenomena associated with an Alu element?

a short stretch of 2-8 nucleotides
Arthrobacter luteus
TATA box-less promoters
occurs in large numbers in primate genomes
mediator dependence
short interspersed elements
there are over one million Alu elements interspersed throughout the human genome

10 Yes or No, A proximal promoter can be found within any core promoter.

Yes
No


Hypotheses

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  1. Various types of repeating boxes containing cytosine and guanine exist.

See also

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{{Anthropology resources}}

{{Medicine resources}}{{Phosphate biochemistry}}