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Gene transcriptions/Boxes/CArGs/Quiz

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CArG boxes is a lecture as part of the gene transcription series.

File:Smooth muscle cell CArG.jpeg
The diagram shows a model for epigenetic regulation of SRF binding to CArG box chromatin. Credit: Oliver G. McDonald, Brian R. Wamhoff, Mark H. Hoofnagle, and Gary K. Owens.

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Quiz

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1 Yes or No, The GCC box is also referred to as the CArG box.

No
Yes

2 The portion of the promoter in which an CArG box is likely to be found is which of the following?

core promoter
proximal promoter
downstream promoter
distal promoter
enhancer

3 Yes or No, The CArG hexaplet repeat is found in the coding region of the human SRF gene.

Yes
No

4 Several promoter elements have been previously identified in eukaryotes, but those cannot account for transcription from most RNA polymerase II-transcribed

5 True or False, Some CArG boxes are located in the distal promoter.

TRUE
FALSE

6 Which of the following is not a transcriptional characteristic of CArG boxes?

located between nucleotides -8 and +2 relative to the transcriptional start site (+1)
G/A/T-G/C+1-G-T/C-G-G-G/A-A-G/C
in eukaryotes
TATA-less genes
a consensus sequence

7 Complete the text:

The AGC box is an

-responsive element found in the

of a large number of

related genes whose expression is

following pathogen attack.

8 Complete the text:

Match up the type of promoter or promoter element with each of the possibilities below:
TATA box - A
initiator element - B
enhancers and inhibitors - C
downstream elements - D
General transcription factor II D - E
ATA box - F
downstream core promoter

.
includes the transcription start site

.
proximal promoter

.
distal promoter

.
core promoter

usually 25 nucleotides upstream

.

9 Which of the following are phenomena associated with CArG boxes?

transcription of A1BG
directs activator-dependent but TFIID-independent transcription
TATA box-less promoters
initiator element
mediator dependence
distal promoter

10 True or False, CArG boxes are found in the promoter regions of at least 1% of human genes.

TRUE
FALSE


Hypotheses

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Main resource: Hypotheses
  1. A1BG is not transcribed using a CArG box.

See also

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{{Anthropology resources}}

{{Medicine resources}}{{Phosphate biochemistry}}

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