Gene transcriptions/Boxes/C/Ds/Quiz

C and D boxes is a lecture as part of the gene transcription series.

This U14 snoRNA from Saccharomyces cerevisiae shows structure and genomic organization. Credit: Dmitry A.Samarsky, Maurille J.Fournier, Robert H.Singer and Edouard Bertrand.

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Quiz edit

  

1 Yes or No, The GCC box is also referred to as the C and D boxes.

No
Yes

2 The portion of the promoter in which C and D boxes are likely to be found is which of the following?

core promoter
proximal promoter
downstream promoter
distal promoter
enhancer

3 Yes or No, The C and D duplet repeat is found in the coding region of the human E2F-4 gene.

Yes
No

4 Several promoter elements have been previously identified in eukaryotes, but those cannot account for transcription from most RNA polymerase II-transcribed

5 True or False, Some C and D boxes are located in the distal promoter.

TRUE
FALSE

6 Which of the following is not a transcriptional characteristic of C and D boxes?

located between nucleotides -8 and +2 relative to the transcriptional start site (+1)
G/A/T-G/C+1-G-T/C-G-G-G/A-A-G/C
in eukaryotes
TATA-less genes
a consensus sequence

7 Complete the text:

A transcript follows one of two possible pathways: (i) a precursor capped with

(open circle) is hypermethylated to yield

(closed circle) and trimmed at the 3' end by

, or (ii) if uncapped, the precursor is

at both ends.

8 Complete the text:

Match up the type of promoter or promoter element with each of the possibilities below:
TATA box - A
initiator element - B
enhancers and inhibitors - C
downstream elements - D
General transcription factor II D - E
ATA box - F
downstream core promoter

.
includes the transcription start site

.
proximal promoter

.
distal promoter

.
core promoter

usually 25 nucleotides upstream

.

9 Which of the following are phenomena associated with C and D boxes?

transcription of A1BG
directs activator-dependent but TFIID-independent transcription
TATA box-less promoters
initiator element
mediator dependence
proximal promoter

10 True or False, C and D boxes are found in the promoter regions of at least 1% of human genes.

TRUE
FALSE


Hypotheses edit

  1. A1BG is not transcribed using C and D boxes.

See also edit

External links edit

{{Anthropology resources}}

{{Medicine resources}}{{Phosphate biochemistry}}