Genes/Expressions

Gene expressions is a suite of genes, and their isoforms, that appear to be biochemically involved in the appearance of a trait.

Gene IDs

"The minimum set of data necessary for a gene record, therefore, is: a unique identifier, or GeneID, assigned by NCBI; a preferred symbol; and either defining sequence information, map information, or official nomenclature from an authority list."

"A unique GeneID is assigned to each new record. There are currently two number generators being used by Gene; one that is assigning values in the range of 7,000,000 – 99,999,999 and another that is assigning values > 100,000,000. Thus the sequence of GeneIDs is expected to have gaps."

Funding

Main resources: Incomes/Funding and Funding

The Cure Brain Cancer Foundation is planning to provide grants of up to $200,000 each to encourage innovative new research. "The Innovation Grant will address this gap by funding higher-risk, big ideas and allow researchers to explore new projects that could improve brain cancer survival, which has barely improved in more than 30 years."

"The Innovation Grant will provide up to $200,000 over two years to researchers with new ideas, including those who work in areas outside of brain cancer."

"It will also enable researchers to produce proof-of-concept data, and establish whether ideas are feasible for ongoing funding."

"Applications for the Innovation Grants are now open and close on 7 July."

Hypotheses

Main resource: Hypotheses

1. The transcription of each gene, or its isoforms, is an opportunity to influence under or over expression.
2. Like simvastatin, the product of some genes that may produce harmful effects can be muted by a biochemical that uses up some of the gene product before it produces unhealthy levels of that product.
3. Gene expressions can be altered such as with the birth control pill that alters the apparent hormone balance to appear as if the woman is pregnant so as to prevent pregnancy.

See also

• Gene project

External links

• GenomeNet KEGG database
• Home - Gene - NCBI
• NCBI All Databases Search
• NCBI Site Search
• WikiDoc The Living Textbook of Medicine